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Research Update End-Year-1 CHF-02403-MOU: Microphthalmia and Delayed Growth Syndrome in the Portuguese Water Dog

Research update for Microphthalmia and Delayed Growth Syndrome project at University of Pennsylvania provides news that project is progressing and DNA samples on file will be submitted for a genome wide association study (GWAS). Researchers are particularly interested in DNA (blood) samples from affected puppies and producer parents. They are also very interested in obtaining samples from bitches and dogs that have been bred to known producers but have never produced any affected puppies themselves. Ideally, these (presumptive “clear”) breeding bitches or dogs would have produced over 16 normal puppies and no affected puppies when bred to known producers (carriers).

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Research Update Mid-Year-1 CHF-02403-MOU: Microphthalmia and Delayed Growth Syndrome in the Portuguese Water Dog

Research update for Microphthalmia and Delayed Growth Syndrome project at University of Pennsylvania provides news that project is progressing and more DNA samples of affected puppies are needed. Preliminary findings indicate males and females can be affected, although females predominate (about 70%). Preliminary pedigree studies suggest an autosomal recessive inheritance.

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Research Update End-Year 3 for Biomarker to Detect Lymphoma Risk, Classify for Treatment and Predict Risk

End-year 3 update of Dr. Jeffery Bryan’s research to discover biomarkers for detection, classification, and treatment of B-cell lymphoma. Progress continues in the researcher’s efforts into this population of B cell lymphomas similar to the aggressive form seen in humans.

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Final Summary Update End-Year 3 – Mapping Genetic Risk Factors for Canine Hip Dysplasia

Final summary update from the end of year 3 of research underway by Dr. Iivanainen of University of Helsinki to hopefully lead to a genetic test to aid breeders in controlling hip dysplasia. Research revealed 30 markers on eight different chromosomes that suggestively associated with the disease.

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