Cruciate ligament rupture (CR) is a common disabling, degenerative condition of the knee. It places a large financial burden on the American public. Inflammation of the stifle and fraying of cruciate ligament fibers, particularly in the cranial cruciate ligament, eventually leads to ligament rupture with associated stifle instability in affected dogs. CR is a moderately heritable, complex disease with genetic and environmental risk.
We proposed to develop a comprehensive method for detection of infectious diseases of dogs, taking the guesswork out of determining which tests to use for diagnosis, and potentially improving disease surveillance because of the comprehensive nature of the test.
Update on improving tick-borne disease therapy from Dr Petersen.
Update on 9/11 Surveillance Study from Dr Otto.
Update on treatment of B-cell lymphoma from Dr Breen.
Continue reading “Research Update CHF Grant 02317 Update End-Year 3: The Role of Complex Translocations Associated with TP53 Somatic Mutations for Aiding Prognosis of Canine Diffuse Large B-Cell Lymphoma”
Update on targeting epigenome for treatment of B-cell lymphoma from Dr McCleary-Wheeler.
Update on clinical trial for hemangiosarcoma treatment from Dr. Dickerson.
Research Update from Dr. Trepanier looking at environmental chemical exposure and cancer.
Update for research to train pathologists to support Golden Retriever Lifetime Study.
Research update from Dr. Volk on prognostic markers for canine mammary cancer.
Continue reading “Research Update Mid-Year 2 CHF 02489: Tumor-permissive Collagen Signatures in Canine Mammary Gland Tumors: Development of Prognostic Markers and Targeted Therapies for Improved Outcomes”