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Research Update Mid-yr 1 CHF 02624: Embracing Polygenicity of Common Complex Disease in Dogs: Genome-wide Association of Cruciate Ligament Rupture

Cruciate ligament rupture (CR) is a common disabling, degenerative condition of the knee. It places a large financial burden on the American public. Inflammation of the stifle and fraying of cruciate ligament fibers, particularly in the cranial cruciate ligament, eventually leads to ligament rupture with associated stifle instability in affected dogs. CR is a moderately heritable, complex disease with genetic and environmental risk.

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Research Update End-yr 1 CHF 02553: Targeted Next Generation Sequencing Panel for Comprehensive Testing of Vector-borne Pathogens

We proposed to develop a comprehensive method for detection of infectious diseases of dogs, taking the guesswork out of determining which tests to use for diagnosis, and potentially improving disease surveillance because of the comprehensive nature of the test.

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