Exploring New Medical Treatments for Cushing’s Syndrome in Dogs

Novel Medical Approach to Canine Hyperadrenocorticism with Melanocortin 2 Receptor (MC2R) Antagonist and Steroidogenic Factor 1 (SF-1) Inverse Agonists

Summary: Researchers will investigate potential new medical treatments for canine Cushing’s syndrome.

Description: Cushing’s syndrome is a hormonal disorder that occurs when the body produces higher than normal levels of the hormone cortisol. Unhealthy levels of cortisol can be triggered by various causes, including pituitary and adrenal gland tumors.

Researchers will assess how two novel compounds affect cortisol production and adrenal tumor growth. Identifying novel medical options will help improve treatment strategies for dogs with Cushing’s syndrome.

Co-sponsored with the Morris Animal Foundation, Grant Number: D15CA-052

Dr. Sara Galac
Utrecht University, The Netherlands