Final Research Update from Dr. Trepanier on genetic and environmental risks of lymphoma in Boxer dogs.
GST genes defend against environmental chemicals that could cause cancer. Our study goals were to
determine whether defective GST genes or specific environmental exposures were associated with
lymphoma in Boxers. While GST variants were not more common in Boxers with lymphoma, we did
find that household proximity within two miles of specific industrial sites were associated with
lymphoma in this population. Final analyses will examine interactions between genotype and
exposures in lymphoma risk.