Soft tissue sarcoma (STS) encompasses a number of neoplasms that are derived from mesenchymal cells including fibrosarcoma, myxosarcoma, hemangiopericytoma, and undifferentiated sarcoma. In the dog, STSs arise frequently in the dermis/subcutis and represent up to 15% of the neoplasms in this location. Our primary aim of this grant was to collect cases of canine STS for histologic and gene expression analysis which we have completed. During all three years of the grant, we had excellent recovery rates from formalin-fixed tissue and have begun to generate sequencing data that can be layered onto the histologic findings and patient demographics.
FINAL, Research Update Transcriptional Profiling of Canine Soft Tissue Sarcoma
