Research Update CHF 02651 Final: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling

We enrolled 30 dogs with mild to moderate atopic dermatitis and 30 healthy control animals in the study. The dogs with atopic dermatitis were treated with either Apoquel® (n=17) or Cytopoint® (n=10), whereas one dog was switched from Apoquel® to Cytopoint®, one dog was treated with prednisone followed by Apoquel®, and one dog was treated with a topical shampoo. Both Apoquel® and Cytopoint® reduced the clinical severity of the skin lesions during 8 weeks of treatment. Continue reading “Research Update CHF 02651 Final: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling”

Research Update CHF 02651 MY2: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling

We enrolled 30 dogs with mild to moderate atopic dermatitis and 30 healthy control animals in the study. The dogs with atopic dermatitis were treated with either Apoquel® (n=17) or Cytopoint® (n=10), whereas one dog was switched from Apoquel® to Cytopoint®, one dog was treated with prednisone followed by Apoquel®, and one dog was treated with a topical shampoo. Continue reading “Research Update CHF 02651 MY2: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling”

Research Update End-yr 1 CHF 02651: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling

Canine atopic dermatitis (CAD) is a common allergic skin disease of dogs with a strong genetic basis. Evidence from human studies suggests that several variants of AD exist with different mechanisms and responses to treatment. Current diagnosis of CAD requires time-consuming procedures that involve a considerable cost to the owner. Therefore, new approaches to identify molecular markers that can help with better diagnosis and management of the disease are warranted. In this study, we are using our tailored methodology for lipid biomarker discovery in CAD.

Continue reading “Research Update End-yr 1 CHF 02651: Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling”