This project will generate a high-quality, reference genome combining the latest technologies, to produce a PWD genome assembly of unprecedented accuracy and completeness. Additionally, this assembly will enable researchers to compare PWD genomes with those of other breeds – unlocking insights into inherited variation that governs morphology, disease risk, and longevity.
Funded Research
- Protective Role for Insulin-like Growth Factor 1 (IGF-1) in Canine Cognitive Dysfunction
- Combining Therapies to Improve Osteosarcoma Treatment
- Mitochondrial Dysfunction and mtDNA Mutations in Canine Hemangiosarcoma: Novel Biomarkers for Early Diagnosis and Personalized Therapy
- A combined sensor approach to examine volatile organic compounds as potential markers of canine hemangiosarcoma
- Engineering a monoclonal antibody therapy for canine mast cell tumors
- Canine Sports Medicine & Rehabilitation Residency Program-UPENN
- The prevalence of Heterobilharzia americana in Portuguese water dogs in the United States
- Building a Portuguese Water Dog Reference Genome to Unlock Breed-Specific Health Insights
- Studying Hemangiosarcoma Subtypes and Treatment Response
- Antiparasitic Treatment of Trypanosoma cruzi-infected Dogs Across Different Stages of Disease for Clinical Cardiac Improvements – the 100-dog Study