Projects

  • Discovery of Novel Biomarkers of Canine Atopic Dermatitis through Lipid Profiling

    Canine atopic dermatitis (CAD) is a common allergic skin disease of dogs with a strong genetic basis. CAD can severely affect the health and well-being of dogs and current diagnosis of CAD requires time-consuming and expensive procedures for the owner. Furthermore, the molecular mechanisms underlying this condition are not well

  • Is Defective Secretion of Antimicrobial Peptides Associated with Reduced Microbicidal Effects in Atopic Keratinocytes?

    This study investigates whether the complications resulting in skin infections experienced by dogs with allergies can be better treated by increasing the secretion of the body’s natural antimicrobial defenses. In this particular case, much work in this direction has been done in human medicine and the researchers at the University

  • Pharmakokinetics and Pharmacodynamics of Hydroxyzine in Healthy Dogs

    Atopic dermatitis is a common allergic skin disease in dogs and humans. Antihistamines are among the most commonly prescribed treatments. Unfortunately, the optimal dosages of commonly used antihistamines have never been scientifically determined, and their effects have not been validated in dogs. Researchers at North Carolina State University wanted to