• Disease Risks Associated with Spay and Neuter: A Breed-Specific, Gender Specific

    This study extends the investigator’s recently completed AKC Canine Health Foundation-funded project studying 12 dog breeds to identify major differences in the degree to which spay or neuter may be related to an increase in joint disorders (hip dysplasia; cranial cruciate ligament tear) and/or cancers (lymphoma; hemangiosarcoma; and mast cell

  • Landmark Clinical Trial to Establish the Evidence-Based Use of Regenerative Medicine to Treat Tendon Injury in Dogs

    This landmark study is being performed by the Veterinary Orthopedic and Sports Medicine (VOSM) Group in Annapolis Junction, MD, whose practioners were instrumental in the formation of the newly recognized veterinary specialty of veterinary sports medicine and rehabilitation. As an active, versatile breed, sports related injuries affect a large number

  • Mapping Refinement of Quantitative Trait Loci for Canine Hip Dysplasia

    Hip dysplasia is one of the most common inherited traits in dogs with an extremely high incidence in some large breeds. It is caused by mutations in multiple genes. In previous studies, investigators discovered the genetic markers that point to the chromosomal regions that harbor the genes that contribute to

  • Genotypic and Phenotypic Dissection of Canine Hip Dysplasia

    A pedigree based on greyhounds and dysplastic Labrador Retrievers will be expanded to find genetic markers associated with the genetic mutations that cause hip dysplasia (HD). Several measures of the inherited traits of the dysplastic hip, age, distraction index, dorsolateral subluxation score and Orthopedic Foundation for Animals hip score, will