Projects

  • Investigation into Diet-Associated Dilated Cardiomyopathy in Dogs

    Dilated cardiomyopathy (DCM) is a serious disease of the heart muscle whereby the heart becomes enlarged with weak contractions. DCM can result inĀ  abnormal heart rhythms, congestive heart failure or sudden death. In dogs, DCM most often occurs in large- and giant-breeds, such as DobermanĀ  Pinschers, Boxers, Irish Wolfhounds, and

  • Use of Gene Therapy to Treat Dilated Cardiomyopathy

    Dilated cardiomyopathy (DCM) is the second most common cause of heart disease in dogs,and medical management of the secondary signs is the only therapeutic option. The outcome for affected dogs depends on the stage of disease and the breed. Once diagnosed, dogs typically exhibit rapid and uniform progression to congestive

  • Juvenile Cardiomyopathy

    Our ultimate goal is to develop a mutation-based test for JDCM. There are several difficulties with JDCM, especially compared with other genetic diseases that affect your breed. Because the diagnosis of affected animals is often made after it is no longer possible to obtain blood or tissue, the most useful