• Exploring New Medical Treatments for Cushing’s Syndrome in Dogs

    Novel Medical Approach to Canine Hyperadrenocorticism with Melanocortin 2 Receptor (MC2R) Antagonist and Steroidogenic Factor 1 (SF-1) Inverse Agonists Summary: Researchers will investigate potential new medical treatments for canine Cushing’s syndrome. Description: Cushing’s syndrome is a hormonal disorder that occurs when the body produces higher than normal levels of the

  • Plasma Cortisol Concentration in Dogs with Pituitary Dependent Hyperadrenocorticism and Atypical Cushing’s Syndrome

    To use a modified version of intermittent samplings to assess whether dogs with atypical Cushing’s syndrome produce increased cortisol over a certain time period. Results Twenty-eight dogs were enrolled in the study to compare cortisol concentrations among healthy dogs, dogs with excess cortisol associated with pituitary dependent Cushing’s syndrome and

  • Assessing Therapeutic Targets for Adrenocortical Tumors

    This study is looking at new therapeutic targets for medical treatment of cortisol-secreting adrenocortical tumors, which cause Cushing’s disease, one of the most common canine endocrine disorders. Co-sponsored with the Morris Animal Foundation, Grant Number: D09CA-913