In the United States, spaying and neutering of dogs and cats is commonly performed to prevent the birth of unwanted pets. However, surgically removing the ovaries or testes may have unexpected consequences. Dogs that have been spayed or neutered have an increased risk for developing obesity, urinary incontinence, hypothyroidism, hyperadrenocorticism, diabetes, cruciate ligament tears, hip dysplasia, and cancer. Lymphoma is three to four times more common in spayed and neutered dogs compared to dogs left intact. In addition, dogs that are neutered before one year of age are three times more likely to develop lymphoma than dogs neutered after one year of age. This funded study is investigating the hormonal and cellular relationships between spaying/neutering and the development of lymphoma so that new treatments will be available in the future to extend life expectancies of dogs with cancer. Continue reading “Research Update CHF 02751-A FINAL: Luteinizing Hormone Receptor Activation Induces Migration and Adhesion in Neoplastic Canine Lymphocytes”
Research Update CHF 02751-A EY1: Luteinizing Hormone Receptor Activation Induces Migration and Adhesion in Neoplastic Canine Lymphocytes
In the United States, spaying and neutering of dogs and cats is commonly performed to prevent the birth of unwanted pets. However, surgically removing the ovaries or testes may have unexpected consequences. Dogs that have been spayed or neutered have an increased risk for developing obesity, urinary incontinence, hypothyroidism, hyperadrenocorticism, diabetes, cruciate ligament tears, hip dysplasia, and cancer. Lymphoma is three to four times more common in spayed and neutered dogs compared to dogs left intact. In addition, dogs that are neutered before one year of age are three times more likely to develop lymphoma than dogs neutered after one year of age. This funded study is investigating the hormonal and cellular relationships between spaying/neutering and the development of lymphoma so that in the future new treatments will be available to extend life expectancies of dogs with cancer.
End-Year-1 Research Update Dr. Kutzler at early spay/neuter and neoplasia.
Update End-Year 2 (Final)- Health Implication of Early Spay Neuter
Summary: Final update on findings at the end-year 2 in a study to develop a generalized understanding of the impact of early spay and neuter on disease risk in dogs. The goal of this project was to evaluate, using one consistent and uniform database at their large veterinary medical center (UC Davis). This update provides conclusions for several medium-to-large breed dogs regarding the impact of early spay/neuter on cancer and musculoskeletal risks. Several additional breeds were evaluated since last update. Additionally, several small breeds were evaluated determining negligible risk with early spay/neuter. Findings indicate risk vary from breed to breed.
Continue reading “Update End-Year 2 (Final)- Health Implication of Early Spay Neuter”
Update Mid-Year 2- Health Implication of Early Spay Neuter
Update on findings at the mid-year 2 in a study to develop a generalized understanding of the impact of early spay and neuter on disease risk in dogs. The goal of this project is to evaluate, using one consistent and uniform database at their large veterinary medical center (UC Davis). This update provides conclusions for several medium-to-large breed dogs regarding the impact of early spay/neuter on cancer and musculoskeletal risks. Additionally, several small breeds were evaluated determining negligible risk with early spay/neuter.Findings indicate risk vary from breed to breed.
Continue reading “Update Mid-Year 2- Health Implication of Early Spay Neuter”
Update End Year 1 – Health Implication of Early Spay Neuter
Update on findings at the end of year 1 in a study to develop a generalized understanding of the impact of early spay and neuter on disease risk in dogs. The goal of this project is to evaluate, using one consistent and uniform database at their large veterinary medical center (UC Davis).
Continue reading “Update End Year 1 – Health Implication of Early Spay Neuter”
