• Disease Risks Associated with Spay and Neuter: A Breed-Specific, Gender Specific

    This study extends the investigator’s recently completed AKC Canine Health Foundation-funded project studying 12 dog breeds to identify major differences in the degree to which spay or neuter may be related to an increase in joint disorders (hip dysplasia; cranial cruciate ligament tear) and/or cancers (lymphoma; hemangiosarcoma; and mast cell

  • Mapping of Genetic Risk Factors for Canine Hip Dysplasia

    Hip dysplasia is an inherited disorder of Portuguese Water Dogs. Currently, breeders utilize phenotypic screening methods in an effort to decrease the incidence of this disease in the breed. However, understanding the genetics of this disorder would have a profound impact on the ability of breeders to prevent this disease

  • Mapping Refinement of Quantitative Trait Loci for Canine Hip Dysplasia

    Hip dysplasia is one of the most common inherited traits in dogs with an extremely high incidence in some large breeds. It is caused by mutations in multiple genes. In previous studies, investigators discovered the genetic markers that point to the chromosomal regions that harbor the genes that contribute to