Diagnostic tests based on the detection of DNA from harmful organisms in clinical samples have revolutionized veterinary medicine in the last decades. Currently, diagnostic panels for several vectorborne diseases (VBDs) are available through universities and private labs in the USA and abroad. Continue reading “Research Update CHF 02528 EY3: Developing a Next Generation Sequencing Diagnostic Platform for Tick-Borne Diseases”
Research Update CHF 02723 EY1: Scientific and Clinical Assessment of Fecal Microbiota Transplant in Obese Dogs: SLIM Study
To date, we have screened 31 dogs for the SLIM study. Of these, 23 have met the inclusion criteria and were enrolled. Of these enrolled dogs, six dogs have completed at least 12 weeks of the 24-week clinical trial. We are averaging 1-2 dogs screening for the study per week. Therefore, we are currently on track to have all dogs enrolled by Fall 2021. Continue reading “Research Update CHF 02723 EY1: Scientific and Clinical Assessment of Fecal Microbiota Transplant in Obese Dogs: SLIM Study”
Research Update CHF 02322 End-Year 4: Analysis of the Health, Behavioral, and Longevity Data Collected in the 9/11 Medical Surveillance Longitudinal Study
Data collected over the 15 years of the 9/11 study represents a massive amount of never before available information on the short and long-term impacts of a search & rescue deployment on the health and behavior of the search dog. Continue reading “Research Update CHF 02322 End-Year 4: Analysis of the Health, Behavioral, and Longevity Data Collected in the 9/11 Medical Surveillance Longitudinal Study”
Research Update CHF 02624 EY2: Embracing Polygenicity of Common Complex Disease in Dogs: Genome-wide Association of Cruciate Ligament Rupture
We have met our Labrador Retriever recruitment for this study over the past six months. We will continue to complete DNA isolation and marker genotyping of the remaining dogs needed for the study as long as the genotyping service remains open under the Covid-19 pandemic. Public engagement with the project continues to be good.
Over the next 6 months, we will focus on finalizing the marker data set for the study for which we do not yet have SNP genotypes. We will then undertake the computing needed to robustly estimate the heritability of cruciate ligament rupture in the Labrador Retriever and further advance prediction of risk of disease using the genomic marker data.
Our final data set is expected to include more than 1,000 Labrador Retriever dogs as promised under the award. We are extremely grateful for the outstanding engagement with this project by the community of Labrador Retriever owners and breeders that we work with.
End-Year-2 Research Update Dr. Muir for polygenicity of cruciate rupture.
Understanding the Genetics of Addison’s Disease in PWDs
April 18, 2021 07:00 ET — The Portuguese Water Dog Foundation is excited to kick off a new research study to investigate the genetics of Addison’s disease — specifically in PWDs! The study will be conducted by Drs. Steven Friedenberg and Leigh Anne Clark and their research team at the University of Minnesota College of Veterinary Medicine and Clemson University.
Lifetime Follow-Up of Canine Hemangiosarcoma
July 13, 2020 09:00 ET — The Portuguese Water Dog Foundation is pleased to support the continuation phase of the Shine On project with the Golden Retriever Foundation, the American Boxer Charitable Foundation and the AKC Canine Health Foundation.
In this continuation phase of the Shine On project, the group of dogs that were originally enrolled in the study and received the Shine On Suspicion (SOS) Test will be followed for their lifetimes to identify any diagnosis of cancer or another chronic disease, the cause of death, and date of death.
Continue reading “Lifetime Follow-Up of Canine Hemangiosarcoma”
Research Update August 2019 CHF-02403-MOU: Microphthalmia and Delayed Growth Syndrome in the Portuguese Water Dog (Puppy Eye Syndrome)
The objective of this study is to A) clinicopathologically and molecularly characterize microphthalmia with delayed growth in the Portuguese Water Dog (PWD) and B) develop a DNA-based test to assist breeders with their breeding programs and avoid producing affected dogs.
Microphthalmia and Delayed Growth Syndrome
February 1, 2017 – The Portuguese Water Dog Foundation is pleased to announce we have signed a Memorandum of Understanding (MOU) along with the Portuguese Water Dog Club of America to collaborate with AKC CHF to jointly fund research at the University of Pennsylvania (UPENN) – Section of Medical Genetics, Pediatrics and Reproduction to better characterize the clinical disorder of syndromic microphthalmia and delayed growth seen in the PWD, commonly known in our breed as Puppy Eye Syndrome (PES). Continue reading “Microphthalmia and Delayed Growth Syndrome”
AKC Canine Health Foundation Announces $432,000 Grant to Fight Cancer in Dogs
RALEIGH, N.C. – The AKC Canine Health Foundation (CHF), a nonprofit organization dedicated to preventing, treating, and curing diseases in all dogs, is pleased to announce the funding of an exciting grant which aims to better understand and prevent hemangiosarcoma, an aggressive form of cancer in dogs. Three groups whose dogs have been affected by this cruel disease — the American Boxer Charitable Foundation, the Golden Retriever Foundation, and the Portuguese Water Dog Foundation — are taking a unique, collaborative stand against cancer by pledging $432,000 to support this research effort.
Continue reading “AKC Canine Health Foundation Announces $432,000 Grant to Fight Cancer in Dogs”
A Novel Approach for the Prevention of Canine Hemangiosarcoma
October 1, 2015 15:00 ET — In an unprecedented collaboration, the Portuguese Water Dog Foundation is pleased and excited to announce that we have signed a Memorandum of Understanding with the Golden Retriever Foundation, the American Boxer Charitable Foundation and the AKC Canine Health Foundation for a joint research project to develop two technologies that will allow researchers to diagnose hemangiosarcoma in the early stages and to treat the disease before it reaches the crisis point.
Continue reading “A Novel Approach for the Prevention of Canine Hemangiosarcoma”
